MFS

PSA Doubling Time – A Significant Prognostic Marker 

PSA Doubling Time – A Significant Prognostic Marker 

Shorter prostate-specific antigen doubling time was significantly associated with shorter metastasis-free survival and overall survival.

The development of metastasis was associated with a 3-fold higher risk of death.

The onset of non-metastatic castrate-resistant prostate cancer and metastatic castrate-resistant prostate cancer was associated with substantial cost increases.

When to Start ADT With A PSA Only Recurrence

Deferred hormone therapy (ADT) for in relapsing M0 (negative scans) prostate cancer patients is associated with prolonged overall survival (OS) measured from the time of local treatment, comparable to OS with salvage ADT in the contemporary experience.

PSA Doubling Time And Proximal PSA Predict Metastasis-Free Survival In Men With Biochemically Recurrent Prostate Cancer After A Radical Prostatectomy

PSA doubling time and the proximal PSA value are excellent predictors of the timing to the formation of metastatic prostate cancer in men who experience a biochemical recurrence (PSA only after surgery).