mHSPC

Differential Treatment Response for Hormone Sensitive Men with Nodal Metastases – Nodal Burden as a Prognostic Biomarker

Differential Treatment Response for Hormone Sensitive Men with Nodal Metastases – Nodal Burden as a Prognostic Biomarker

Men with prostate cancer with both nodal and bone metastases due worse with ADT plus docetaxel chemotherapy than men with only bone metastases. In addition, increased nodal metastases burden is a negative prognostic biomarker.

ADT With and Without Xtandi in Men with Metastatic Hormone Sensitive Prostate Cancer: The ARCHES Trial

After a median follow-up of 14.4 months, the men who had Xtandi along with ADT experienced an improved radiographic progression-free survival advantage over those who had only ADT, regardless of their prior treatment.